Altered Intracortical Inhibition in Chronic Traumatic Diffuse Axonal Injury
نویسندگان
چکیده
1Department of Neurology, School of Medicine, University of São Paulo (USP), São Paulo, Brazil, 2School of Medicine, Universidade da Cidade de São Paulo (UNICID), São Paulo, Brazil, 3Service of Interdisciplinary Neuromodulation, Institute of Psychiatry, Hospital das Clínicas HCFMUSP, University of São Paulo (USP), São Paulo, Brazil, 4Division of Psychology, Hospital das Clínicas HCFMUSP, University of São Paulo (USP), São Paulo, Brazil
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Traumatic brain injury is a nondegenerative, noncongenital insult to the brain caused by external mechanical forces. Recent studies suggest that even mild concussions—if repetitive—can trigger progressive neurological degeneration, a condition that is now widely known as ‘‘chronic traumatic encephalopathy’’ (1). Notably, chronic traumatic encephalopathy continues to progress even decades after ...
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Diffuse traumatic brain injury refers to widespread pattern of injury throughout the brain caused by traumatic disruption of nerve cells, with particular injury to the axons [1]. There are four principal types of traumatic brain injury: diffuse vascular injury, diffuse axonal injury, hypoxic-ischemic encephalopathy and diffuse brain swelling [2]. Clinically, DAI is characterized by generalized ...
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